Antibiotic Resistance of Campylobacter jejuni and C. coli Isolated from Children with Diarrhea in Thailand and Japan

Japanese Journal of Infectious Diseases

Hiroshi Ushijima⁵  Aksara Thongprachum⁵  Satoshi Hayakawa⁵  Ngan Thi Kim Pham⁵  Yuko Shimizu-Onda⁵  Shoko Okitsu⁵  Quang Duy Trinh⁵  Shihoko Komine-Aizawa⁵  Pattara Khamrin¹  Shuichi Nishimura⁴  Niwat Maneekarn¹  Nuthapong Ukarapol²  Dinh Nguyen Tran⁵  Tipachan Kongsricharoern³ 

[1] Department of Microbiology, Faculty of Medicine, Chiang Mai University;Department of Pediatrics, Faculty of Medicine, Chiang Mai University;Pediatric Hematology Unit, Nakornping Hospital;Nishimura Clinic;Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine

关键词: Campylobacter;    antibiotic resistance;    Thailand;    Japan;   

DOI  :  10.7883/yoken.JJID.2014.582

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

References(15)Cited-By(1)A total of 29 Campylobacter jejuni and C. coli strains were isolated from Thai and Japanese children with diarrhea using the Loop-mediated Isothermal Amplification method. The samples were evaluated for mutations in gyrA and 23S rRNA in order to assess resistance against fluoroquinolones and macrolides, respectively. Among the isolated strains, 9 (8 C. jejuni and 1 C. coli) were from Thai children, and the other 20 (C. jejuni) were isolated from Japanese children. High fluoroquinolone resistance rates were observed in Thai (66.7%) and Japanese (90%) children. Macrolide resistance was not observed in Japanese children but was observed at a considerable rate of 12.5% of C. jejuni isolated in the Thai cohort. The results indicate that continuous monitoring of resistance of Campylobacter strains to fluoroquinolones and macrolides is definitely necessary.

【 授权许可】

Unknown