Alternate Exon in the 5'-Untranslated Region of the Human ACTH Receptor Gene

Endocrine Journal

MITSUMASA KUBO²  TATSUYA ISHIZUKA¹  KAZUHIKO TAKANO¹  HIROMICHI KIJIMA¹  AKIKO TAKANO¹  CHIKARA SHIMIZU¹  TAKAO KOIKE¹ 

[1] Department of Medicine II, Hokkaido University School of Medicine;Health Administration Center, Hokkaido University of Education

关键词: Gene structure;    Alternative splicing;    ACTH receptor;    Adrenal gland;    Human;   

DOI  :  10.1507/endocrj.47.543

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(14)Cited-By(1)The human ACTH receptor (ACTH-R) gene consists of two exons; the first encodes the 5'-untranslated region (UTR) and the second encodes part of the 5'-UTR, the entire coding region, and the whole of the 3'-UTR. While investigating the transcription initiation site of the human ACTH-R gene by 5'-rapid amplification of cDNA ends, we found a 157-bp alternate exon in the 5'-UTR. This newly identified exon was irrelevant to the alternate exon in the mouse ACTH-R gene which we reported previously.

【 授权许可】

Unknown