Journal of Veterinary Medical Science | |
Prevalence of Circulating Antibodies to p10, a Non-structural Protein of the Borna Disease Virus in Cats with Ataxia | |
Kazuyoshi IKUTA1  Masami MOCHIZUKI3  Atsuo OUCHI4  Takeshi KOBAYASHI1  Masahiko KISHI4  Patrick K. LAI2  Tahir H. MALIK2  | |
[1] Research Institute for Microbial Diseases, Osaka University;Department of Biosciences, Salem International University;Laboratory of Clinical Microbiology, Kyoritsu Seiyaku Corporation;Tsukuba Central Laboratories, Kyoritsu Seiyaku Corporation | |
关键词: anti-BDV antibody; ataxia; Borna disease virus; feline.; | |
DOI : 10.1292/jvms.63.1279 | |
学科分类:兽医学 | |
来源: Japanese Society of Veterinary Science | |
【 摘 要 】
References(45)Cited-By(6)Japanese domestic cats were surveyed for circulating antibodies to the p10 and p24 proteins of the Borna disease virus (BDV) by Western blotting. Twenty-four of 52 cats (46.2%) with ataxia and other neurologic symptoms of unknown cause were positive for antibodies to BDV p10 and/or p24. In contrast, cats without neurological symptoms gave a significantly lower prevalence of anti-BDV antibodies to p10 and/or p24 (36 of 152 cats, 23.7%). Thirty specific pathogen-free (SPF) cats tested as controls were uniformly negative to BDV p10 and p24 antigens. These results suggest that BDV may play a role in ataxia in cats. Additionally, our results suggest that it is necessary to use both p10 and p24 as antigens to detect circulating antibodies to BDV in cats.
【 授权许可】
Unknown
【 预 览 】
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RO201911300833709ZK.pdf | 132KB | download |