Present Status of Adjuvant Chemotherapy for Elderly Breast Cancer Patients

Breast care

Sibylle Loibl¹  Mattea Reinisch¹ 

[1] aGerman Breast Group, Neu-Isenburg, Germany

关键词: Adjuvant chemotherapy;    Elderly patients;    Breast cancer;   

DOI  :  10.1159/000345867

学科分类：泌尿医学

来源: S Karger AG

【 摘 要 】

Elderly breast cancer patients are underrepresented in clinical trials, leading to a lack of knowledge regarding their tolerance of modern chemotherapy regimens. In addition, physicians are often reluctant to treat older patients with chemotherapy due to potential side effects. This article summarizes the up-to-date literature on chemotherapy in elderly patients with breast cancer, evaluates the impact of the patients’ comorbidities and treatment alterations and aims to encourage treating patients adequately according to their disease in combination with the biological age rather than the chronological age alone. Finally, a short overview is given of the recruiting studies in Europe evaluating chemotherapy in elderly patients.

【 授权许可】

Unknown