Incidence and predictors of right paraesophageal lymph node metastasis of N0 papillary thyroid carcinoma located in the right lobe

Endocrine Journal

Yuuki Takamura¹  Akihiro Miya¹  Minoru Kihara¹  Yasuhiro Ito¹  Kaoru Kobayashi¹  Mitsuhiro Fukushima¹  Takuya Higashiyama¹  Akira Miyauchi¹ 

[1] Department of Surgery, Kuma Hospital, Kobe 650-0011, Japan

关键词: Papillary thyroid carcinoma;    Paraesophageal node;    Lymph node metastasis;   

DOI  :  10.1507/endocrj.EJ12-0362

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(12)Cited-By(4)Papillary thyroid carcinoma (PTC) frequently metastasizes to the regional lymph nodes and, thus, guidelines edited by Japan Association of Endocrine Surgeons/Japanese Society of Thyroid Surgery routinely recommend central node dissection even for patients with no clinically detectable node metastasis (N0).However, in the central compartment, metastasis to the right paraesophageal node has not been intensively investigated.We investigated the incidence and predictors of right paraesophageal node metastasis based on pre- and intraoperative findings in 922 patients with N0 PTC in the right lobe.Fourteen percent of patients were microscopically positive for right paraesophageal node metastasis, and the incidence was smaller than that for pre- and right paratracheal node metastasis (46%).On multivariate analysis, a tumor size ≥ 2 cm and significant extrathyroid extension were independent predictors of metastasis.Microscopically pre- and right paratracheal node-positive PTC more often (p < 0.0001) metastasized to the right paraesophageal node.Taken together, in N0 PTC in the right lobe, right paraesophageal node dissection should be considered in tumors 2 cm or larger and/or with significant extrathyroid extension, or when pre- and right paratracheal node metastasis is suspected based on the intraoperative findings.

【 授权许可】

Unknown