Static and dynamic prognostic factors of papillary thyroid carcinoma [Review]

Endocrine Journal

Akihiro Miya¹  Minoru Kihara¹  Yasuhiro Ito¹  Kaoru Kobayashi¹  Akira Miyauchi¹ 

[1] Department of Surgery, Kuma Hospital, Kobe 650-0011, Japan

关键词: Prognostic factors;    Papillary thyroid carcinoma;    Thyroglobulin;    Thyroglobulin antibody;    Lymph node metastasis;   

DOI  :  10.1507/endocrj.EJ14-0303

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(53)Cited-By(1)The two types of prognostic factors of papillary thyroid carcinoma (PTC) are static and dynamic.The following static prognostic factors have been conventionally adopted: age, tumor size, extrathyroid extension, lymph node metastasis, and distant metastasis based on pre-, intra- and post-operative findings.These factors are useful to decide therapeutic strategies for PTC patients, including the extent of surgery and radioactive iodine (RAI) ablation.However, even the combination of these factors evaluated pathologically postoperatively is not good enough at predicting recurrence in clinical settings.The dynamic prognostic factors of changes in serum thyroglobulin (Tg) and thyroglobulin antibody (TgAb) values in patients who have undergone a total thyroidectomy are important to evaluate the progression of carcinoma recurrence and to predict patients’ cause-specific survival, regardless of their backgrounds and the clinicopathological features of their PTC.Dynamic prognostic factors are superior to static prognostic factors in terms of expressing the condition of recurrence on a real-time basis.

【 授权许可】

Unknown