Trends over time in the size and quality of randomised controlled trials of interventions for chronic low-back pain

European Spine Journal

Sidney M. Rubinstein³  Nicholas Henschke³  Ton Kuijpers¹  Bart W. Koes⁴  Marienke van Middelkoop⁴  Raymond Ostelo²  Maurits W. van Tulder²  Arianne Verhagen⁴ 

[1] Dutch Institute for Healthcare Improvement CBO, Utrecht, The Netherlands;Department of Health Sciences, Faculty of Earth and Life Sciences, VU University, Amsterdam, The Netherlands;EMGO+ Institute for Health and Care Research, Amsterdam, The Netherlands;Department of General Practice, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands

关键词: Back pain;    Bias;    Methodology;    Randomised trials;   

DOI  :  10.1007/s00586-011-2023-z

学科分类：骨科学

来源: Springer

【 摘 要 】

Previous reviews of randomised controlled trials (RCTs) for low-back pain (LBP) have failed to identify any positive trend in study quality with more recent years of publication. This study aimed to identify and describe trends over time in the study design characteristics and risk of bias in chronic LBP trials performed over the past 30 years.

【 授权许可】

Unknown