Essential Thrombocythemia in a Dog

Journal of Veterinary Medical Science

Koichi OHNO¹  Teppei NAGASAKI²  Hajime TSUJIMOTO¹  Kuniyoshi YASUKAWA²  Tetsuya SHIMODA²  Yasuhito FUJINO¹  Hidefumi MATUMOTO²  Shingo MATSUMURA²  Takeshi MIZUKOSHI² 

[1] Department of Veterinary Internal Medicine, Graduate School of Agricultural and Lifesciences, The University of Tokyo;Sanyo Animal Medical Center

关键词: busulfan;    essential thrombocythemia;    seizure;   

DOI  :  10.1292/jvms.68.1203

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(19)Cited-By(2)A two-year old male Welsh Corgi was referred for persistent thrombocytosis and occasional seizure. Hematological findings indicated marked thrombocytosis, eosinophilia, basophilia and moderate anemia. Bone marrow examination revealed marked megakaryocytic hyperplasia with morphologic abnormality. A diagnosis of essential thrombocythemia was made and the treatment was initiated with combination chemotherapy and maintained by prednisolone and busulfan. The dog successfully achieved complete remission on 100 days after initial presentation and has been good in health without chemotherapy since then.

【 授权许可】

Unknown