Effect of L-glutamine levels in piglets diets challenged with Escherichia coli lipopolysacharides

Revista MVZ Córdoba

dos Santos, Andréa³  Nogueira, Eduardo⁴  da Silva, Caio¹  Pardo L, Arturo¹  Poveda P, Angela³  Venâncio, Emerson¹  Arantes, Vânia² 

[1] Londrina State University, Londrina, Brasil;Federal University of Mato Grosso, Cuiabá, Brasil;Federal University of Mato Grosso, Rondonópolis, Brasil;Ajinomoto of Brasil, São Paulo, Brasil

关键词: Animal performance;    immunity;    leukocytes;    stress (Source: Agrovoc);   

DOI  :  

学科分类：兽医学

来源: Universidad de Cordoba * Facultad de Medicina Veterinaria y Zootecnia

【 摘 要 】

Objective. To evaluate the effect of different levels of L-glutamine on weaned and immunologically challenged piglets with Escherichia coli lipopolysaccharides (LPS) on performance parameters, serum cortisol and defense cells. Materials and methods. Four levels of L -glutamine were evaluated (0, 1.0, 1.5, 2.0%) as well as the addition, or no addition, of LPS (0.3µg). 96 piglets were used (48 castrated males and 48 females) of Agroceres x PenArlan lineage, with an initial age of 21 days and 6.06±0.852 kg live weight. An experimental design was used on randomized blocks in a factorial setting 4 x 2 (levels of L- glutamine with or without challenge). Results. Cubic effect was shown for daily weight gain of unchallenged animals, and was better with the addition of 0.41% L- glutamine. Feed conversion improved with increased levels of L -glutamine for challenged animals. In the evaluation of defense cells, there was interaction of leukocytes with the levels of L- glutamine and the immune challenge. Eosinophils and lymphocytes showed a quadratic effect for the levels of L -glutamine, with a maximum value of 1.30% and 0.5%, respectively. Conclusions. L -glutamine supplementation of up to 2% in the diet improves feed conversion and favors the immune serum of weaned piglets challenged with LPS of E. coli.

【 授权许可】

Unknown