British Journal of General Practice | |
Hepatitis B vaccination and injecting drug users | |
John Budd1  Rob Elton1  Roy Robertson1  | |
[1] Edinburgh Drug Addiction Study | |
关键词: hepatitis B; hepatitis C; HIV; vaccination; IV drug users; immunology; serology; | |
DOI : | |
学科分类:卫生学 | |
来源: Royal College of General Practitioners | |
【 摘 要 】
This study seeks to test the feasibility of vaccinating injecting drug users for hepatitis B in primary care and to identify predictors of poor immune response. Two hundred and seventy-five injecting drug users were identified from the case notes of a large general practice in an area of high multiple deprivation in northwest Edinburgh and, where appropriate, offered hepatitis B vaccination followed by a post-vaccination serological test. We concluded that hepatitis B vaccination of drug users in primary care is both feasible and effective. This study was unable to identify a group at risk of vaccine failure, however, it found post-vaccination serological testing to be problematic and potentially misleading. Therefore, we would not recommend its routine use in a primary care setting. Significantly, prolonged primary courses were not associated with reduced efficacy. The findings indicate that an appropriate vaccination schedule for primary care should be flexible to maximise compliance.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201911300144733ZK.pdf | 73KB | download |