Accuracy of Prognostic and Predictive Markers in Core Needle Breast Biopsies Compared with Excisional Specimens

Breast care

Mohammad Samadi¹  Ali Jangjoo¹  Mohsen Aliakbaian¹  Mohammad T. Shakeri¹  Mohammad Motamedolshariati¹  Bahram Memar¹ 

[1] aVascular and Endovascular Surgery Research Center, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

关键词: Prognostic factors;    Breast cancer;    Core needle biopsy;   

DOI  :  10.1159/000360787

学科分类：泌尿医学

来源: S Karger AG

【 摘 要 】

Core needle biopsy (CNB) is widely accepted for preoperative diagnosis of breast cancer and sometimes can be the only way of providing a suitable specimen for prognostic and predictive marker studies prior to neoadjuvant treatment. The purpose of this study was to evaluate the accuracy of CNB by comparing histological tumor type and grade as well as estrogen receptor (ER), progesterone receptor (PR), p53, and HER2/ neu status by immunohistochemistry in CNB and excisional surgical specimens.

【 授权许可】

Unknown