Jordan Journal of Biological Sciences | |
The Relationship between Helicobacter pylori (H. pylori) and Atopy and Allergic Diseases | |
Eman M. Albataineh1  | |
关键词: Helicobacter pylori; Asthma; Childhood Asthma; Jordan; | |
DOI : | |
学科分类:生物科学(综合) | |
来源: Hashemite University, Deanship of Research and Higher Studies | |
【 摘 要 】
Reduced exposures to gastrointestinal microbiota have been proposed as an explanation for the increase in the prevalence ofallergic diseases. The aim of this research is to study the relationship between H. pylori and atopy/allergic diseases. 210children (aged 2-16 years old) with or without allergic diseases were selected from the Asthma Clinic in Al-KarakGovernmental Hospital to participate in the study. Their parents were asked to fill out questionnaires. An Atopy test was doneand the serum IgG antibodies to the H. pylori antigens were measured. Out of the 210 children, 38 were H. pylori-positivepatients (18.1%), 31 cases (14.1 %) were atopic, and 60 patients (28.6%) were asthmatic. Out of the 38 H. pylori positivepatients, only one case (2.6 %) was atopic. A significant negative association between H pylori and asthma was observed in theless than nine-year-old age group (p value = 0.007). The negative association between H. pylori and atopy was significant inmales (p value = 0.02).The factors that best predict asthma include a family history of asthma, positive H. pylori, positiveallergy test (p values of <0.005). Our findings showed that there is an inverse correlation between H. pylori and atopy.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
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RO201911048881719ZK.pdf | 209KB | download |