Functional Imaging and Optogenetics in Drosophila

Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation

Julie H. Simpson^1¹  Loren L. Looger^2² 

[1] Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, California 93106-9625^1;Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147^2

关键词: nervous system;    optogenetics;    connectivity;    Drosophila;    functional imaging;    methods;    behavior;    FlyBook;   

DOI  :  10.1534/genetics.117.300228

学科分类：医学（综合）

来源: Genetics Society of America

【 摘 要 】

Understanding how activity patterns in specific neural circuits coordinate an animal’s behavior remains a key area of neuroscience research. Genetic tools and a brain of tractable complexity make Drosophila a premier model organism for these studies. Here, we review the wealth of reagents available to map and manipulate neuronal activity with light.

【 授权许可】

CC BY