Costs and quality of life by disability among people with multiple sclerosis: a register-based study in Sweden

Multiple Sclerosis Journal – Experimental, Translational and Clinical

HannaGyllensten¹ 

关键词: Multiple sclerosis;    cost of illness;    healthcare costs;    registries;    sick leave;    health-related quality of life;    disability evaluation;    disease progression;   

DOI  :  10.1177/2055217318783352

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

BackgroundPopulation-based estimates of costs of illness and health-related quality of life, by disability levels among people with multiple sclerosis, are lacking.ObjectivesTo estimate the annual costs of illness and health-related quality of life, by disability levels, among multiple sclerosis patients, 21–64 years of age.MethodsMicrodata from Swedish nationwide registers were linked to estimate the prevalence-based costs of illness in 2013, including direct costs (prescription drug use and specialised healthcare) and indirect costs (calculated using sick leave and disability pension), and health-related quality of life (estimated from the EQ-5D). Disability level was measured by the Expanded Disability Status Scale (EDSS).ResultsAmong 8906 multiple sclerosis patients, EDSS 0.0–3.5 and 7.0–9.5 were associated with mean indirect costs of SEK 117,609 and 461,357, respectively, whereas direct costs were similar between the categories (SEK 117,423 and 102,714, respectively). Prescription drug costs represen...

【 授权许可】

CC BY-NC