Detection of Zinc(II) by a Fluorescence Chemosensor Based on Benzofuran in Aqueous Media and Live Cells

Bulletin of the Korean Chemical Society

Ahran Kim¹  Hyo Jung Jang² 

[1] Department of Chemistry KAIST Daejeon 34141 South Korea;Department of Fine Chemistry Seoul National University of Science and Technology (SNUT) Seoul 138740 South Korea

关键词: Cell imaging;    Fluorescence sensor;    Zinc;    Theoretical calculations;   

DOI  :  10.1002/bkcs.11608

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A fluorescence chemosensor HBC ((E)‐3‐((2‐hydroxybenzylidene)amino)benzofuran‐2‐carboxamide) for detection of Zn2+ was designed by the condensation combination of 3‐aminobenzofuran‐2‐carboxamide and salicylaldehyde. Sensor HBC showed an excellent selective “off–on” fluorescent response toward Zn2+. Detection limit (1.08 μM) for Zn2+ was much lower than the WHO standard (76.0 μM). Importantly, HBC could recognize and quantify Zn2+ in real samples and live cells. Detection process of HBC for Zn2+ was explained by ESI‐mass, Job plot, UV–Vis and 1H NMR titrations, and theoretical calculations.

【 授权许可】

Unknown