Auditory brainstem function in women with vestibular migraine: a controlled study

BMC Neurology

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[1] 0000 0001 0514 7202, grid.411249.b, Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Universidade Federal de São Paulo, São Paulo, Brazil;0000 0001 2149 6891, grid.412529.9, Divisão de Educação e Reabilitação dos Distúrbios da Comunicação (DERDIC), Pontíficia Universidade Catolica de São Paulo, São Paulo, Brazil;Audio-Vestibular Clinic, Vancouver, Canada;

关键词: Migraine;    Vertigo;    Auditory evoked potentials;    Brainstem;    Hyperacusis;   

DOI  :  10.1186/s12883-019-1368-5

来源: publisher

【 摘 要 】

BackgroundVestibular migraine (VM) has been recognized as a diagnostic entity over the past three decades. It affects up to 1% of the general population and 7% of patients seen in dizziness clinics. It is still underdiagnosed; consequently, it is important to conduct clinical studies that address diagnostic indicators of VM. The aim of this study was to assess auditory brainstem function in women with vestibular migraine using electrophysiological testing, contralateral acoustic reflex and loudness discomfort level.MethodsThe study group consisted of 29 women with vestibular migraine in the interictal period, and the control group comprised 25 healthy women. Auditory brainstem response, frequency following response, binaural interaction component and assessment of contralateral efferent suppression were performed. The threshold of loudness discomfort and the contralateral acoustic reflex were also investigated. The results were compared between the groups.ResultsThere was a statistically significant difference between the groups in the frequency following response and the loudness discomfort level.ConclusionsThe current study suggested that temporal auditory processing and loudness discomfort levels are altered in VM patients during the interictal period, indicating that these measures may be useful as diagnostic criteria.

【 授权许可】

CC BY