Copper‐catalyzed Decarboxylative Hydroboration: Synthesis of Vinyl Boronic Esters

Bulletin of the Korean Chemical Society

Sung Kim¹  Kyungsu Na¹  Han‐¹  Francis Mariaraj Irudayanathan¹  Gabriel Charles Edwin Raja¹ 

[1] Department of Chemistry Chonnam National University Gwangju 61186 Republic of Korea

关键词: Copper;    Decarboxylative borylation;    Arylalkynyl carboxylic acids;    Vinyl boronates;    Hydroboration;   

DOI  :  10.1002/bkcs.10706

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Vinyl boronic esters were synthesized from aryl alkynyl carboxylic acids and bis(pinacolato)diboron using a copper‐catalyzed decarboxylative reaction. The reaction was conducted with CuI (10 mol%), bis‐[2‐(diphenylphosphino)phenyl]ether(20 mol%), and LiOMe (20 mol%) in DMSO at 50 °C for 16 h. This method provided the desired vinyl boronic esters in good‐to‐moderate yields and showed good functional group tolerance.

【 授权许可】

Unknown