The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells

Cancer Communications

Yi Zhou¹  Zhen-Hai Lu²  Jiang-Xue Wu³  Ran-Yi Liu⁴  Chun-Mei Kuang⁴  Shuai Chen⁴  Wen Ye⁴  Wu-Ying Du⁴  Wen-Lin Huang⁴  Xiang Fu⁴  Zhi-Zhong Pan⁵ 

[1] Department of Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China;Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, USA;Department of Radio-chemotherapy, Shangrao People’State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China;s Hospital, Shangrao, China

关键词: Ankyrin repeat and SOCS box protein 3 (ASB3);    Colorectal cancer;    Epithelial-mesenchymal transition;    Cell proliferation;    Tumor metastasis;   

DOI  :  10.1186/s40880-017-0180-0

学科分类：肿瘤学

来源: Springer

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