Biodegradation of Paracetamol by Native Bacterial Strains Isolated from Yemeni Pharmaceutical Wastewater Plant in Sana’a

Chronicles of Pharmaceutical Science

Ali G AL-Kaf¹  Wadhah H Edrees*²  Qais Y Abdullah³ 

[1] Chemistry Department, Faculty of Science, Sana'a University, Yemen;Medicinal Chemistry Department, Faculty of Pharmacy, Sana'a University, Yemen;Biology Department, Faculty of Science, Sana'a University, Yemen

关键词: Bacteria;    Biodegradation;    Isolation;    Paracetamol;    Physiological Characterization;   

DOI  :  

学科分类：医学（综合）

来源: Scientia Ricerca

【 摘 要 】

Paracetamol has emerged as an important environment pollutant due to its extensive usage. This study amid to isolate, identify, and characterize of a native Paracetamol-degrading bacteria from the contaminated site of pharmaceutical wastewater at Sana'a City, Yemen. The bacteria were isolated and purified from wastewater samples by using the enrichment media and selective medium. The isolated bacteria were identified according to phenotypic and genotypic characterizations. The results showed that the two bacterial strains were isolated from a contaminated site. These strains were signed as an STB2 and STB4 and identified as Pseudomonas aeruginosa strain ATCC 10145 with similarity 88% and 97%, respectively. Also, the environmental factors, carbon, and energy sources were observed to influence the biodegradation rate of Paracetamol. However, it was found that the 79.4% and 88.4% of 3000 mg/L Paracetamol were degraded by strain STB2 and STB4, respectively, in 120 h. The results performed that the degradation potential of the two isolated bacterial strains possibly played a major active role in the Paracetamol removal processes.

【 授权许可】

CC BY