EELS from organic crystalline materials

Electron Microscopy and Analysis Group Conference 2013

Brydson, R.^1 ; Eddleston, M.D.^2 ; Jones, W.^2 ; Seabourne, C.R.^1 ; Hondow, N.^1

Institute for Materials Research, SPEME, University of Leeds, LS2 9JT Leeds, United Kingdom^1

Department of Chemistry, University of Cambridge, Lensfield Road, CB2 1EW Cambridge, United Kingdom^2

关键词: Chemical compositions;    Electron loss;    Light elements;    Near edge structure;    Paracetamol;    Pharmaceutical materials;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/522/1/012060/pdf
DOI  :  10.1088/1742-6596/522/1/012060

来源: IOP

【 摘 要 】

We report the use of the electron energy loss spectroscopy (EELS) for providing light element chemical composition information from organic, crystalline pharmaceutical materials including theophylline and paracetamol and discuss how this type of data can complement transmission electron microscopy (TEM) imaging and electron diffraction when investigating polymorphism. We also discuss the potential for the extraction of bonding information using electron loss near-edge structure (ELNES).