期刊论文详细信息
Animal Models and Experimental Medicine | |
The intestinal microbiome and Alzheimer's disease: A review | |
Ling Zhang1  Chuan Qin1  Hua Zhu1  Zhuo Li1  | |
[1] Institute of Medical Laboratory Animal Science Chinese Academy of Medical Sciences & Comparative Medical Center Peking Union Medical College Beijing China | |
关键词: Alzheimer's disease; blood‐; brain barrier; intestinal barrier; intestinal microbiota; neuroinflammation; | |
DOI : 10.1002/ame2.12033 | |
学科分类:医学(综合) | |
来源: Wiley | |
【 摘 要 】
Alzheimer's disease (AD) is an increasingly common neurodegenerative disease. Since the intestinal microbiome is closely related to nervous system diseases, alterations in the composition of intestinal microbiota could potentially contribute to the pathophysiology of AD. However, how the initial interactions with intestinal microbes alter events later in life, such as during neurodegenerative diseases, is still unclear. This review summarizes what is known about the relationship between the intestinal microbiome and AD.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
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RO201904027154367ZK.pdf | 1588KB | download |