Case of a miniature dachshund with a primitive neuroectodermal tumor confinedto the forebrain region treated with a combination of surgery andchemotherapy

The Journal of Veterinary Medical Science

Kazuyuki UCHIDA¹  Akihiko YAMADA²  Satoru MATSUNAGA³  Yuya NAKAMOTO³  Tsuyoshi OZAWA⁴ 

[1] Department of Bioartificial Organs, Institute forFrontier Medical Sciences, Kyoto University, 53, Kawahara-cho, Sakyo-ku, Kyoto-shi,Kyoto 606–8507, Japan;Japan Animal Referral Medical Center, 2-5–8, Kuji,Takatsu-ku, Kawasaki, Kanagawa 213–0032, Japan;Kyoto Animal Referral Medical Center, 208–4, Shinarami,Tai, Kumiyama-cho, Kuze-gun, Kyoto 613–0036, Japan;Nishi-kyogoku Animal Hospital, 43, Nishimaruta-machi,Nishi-kyogoku, Ukyo-ku, Kyoto-shi, Kyoto 615–0862, Japan

关键词: canine;    chemotherapy;    MRI;    primitive neuroectodermal tumor;    surgery;   

DOI  :  10.1292/jvms.16-0273

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

A miniature dachshund aged 9 years and 7 months with a history of polyuria/polydipsia anddepression was referred. General physical and neurological examinations revealed noobvious abnormalities. MRI of the brain revealed a large space-occupying lesion in theleft frontal lobe. This was surgically removed and pathologically diagnosed as a primitiveneuroectodermal tumor (PNET). Although the clinical signs had been improved, follow-up MRIrevealed recurrence of the tumor. Lomustine was administered, but 1 year after surgery,the dog exhibited cluster seizures and died. This is the first reported case of a dog withPNET confined to the forebrain region treated by surgical resection in combination withchemotherapy, as observed by repeated follow-up MRI.

【 授权许可】

Unknown