Successful management of testicular primitive neuroectodermal tumor with multiple bone metastases

IJU Case Reports

article

Takuya Takasawa¹  Tomonori Minagawa¹  Takahisa Domen¹  Toshirou Fukushima⁴  Yu Fujii⁵  Mai Iwaya⁶  Tomonobu Koizumi⁴  Teruyuki Ogawa¹  Osamu Ishizuka¹ 

[1] Department of Urology, Shinshu University School of Medicine;Contribution: Writing - review & editing;Contribution: Resources;Department of Hematology and Medical Oncology, Shinshu University School of Medicine;Department of Neurosurgery, Shinshu University School of Medicine;Department of Laboratory Medicine, Shinshu University Hospital

关键词: chemotherapy;    germ cell tumor;    malignant transformation of teratoma;    primitive neuroectodermal tumor;   

DOI  :  10.1002/iju5.12431

学科分类：社会科学、人文和艺术（综合）

来源: Wiley

【 摘 要 】

Introduction Germ cell tumor with malignant transformation is extremely rare. We present a case of testicular primitive neuroectodermal tumor with multiple metastases that was effectively managed by surgery, irradiation, and second-line chemotherapy. Case presentation A 22-year-old man was diagnosed as having teratoma including primitive neuroectodermal tumor with lymph node and multiple bone metastases. Five months afterwards the first-line therapy, his skull metastasis recurred. Vincristine, doxorubicin, and cyclophosphamide therapy followed by vincristine, actinomycin D, and cyclophosphamide therapy was given as second-line chemotherapy. Computed tomography revealed no disease progression 3 months after the treatments. Conclusion Metastatic primitive neuroectodermal tumor may be successfully managed by multidisciplinary cancer treatment.

【 授权许可】

CC BY|CC BY-NC|CC BY-NC-ND