Analysis of abnormal cervical cytology in Papanicolaou smears at tertiary care center – A retrospective study

International Journal of Biomedical and Advance Research

Bhavika Vaghela ; Vikas K. Vaghela ; Pravina M. Santwani

关键词: s Pap smear;    Cervical cancer;    The Bethesda System;   

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Objective: Cervical cancer is the second most common cancer in women worldwide after breast cancer, and in developing countries, the leading cause of death by cancer. It is one of the most preventable and curable of all cancers. Most women are never undergoing a cervical Pap smear screening. The Objective is to study the role of Pap smear in detecting premalignant and malignant lesions as well as nonneoplastic lesions of cervix and to determine the prevalence of various lesions.  Methods: This retrospective study of 500 women with age group 18 to 90 years was carried out over a 2 years at cytology section of pathology department, M.P.Shah medical college, Jamnagar. This study had been divided into 2 groups. Group I included study of 400 women who attended gynaecological clinic at GGH hospital Jamnagar and Group II included study of 100 women who attended Pap smear screening camp at Air force hospital, Jamnagar. Pap smears were prepared and after fixation and staining, each smear was carefully examined. Results: In this study, Low-grade squamous intraepithelial lesions was the most common with 62 cases (12.4%) followed by High-grade squamous intraepithelial lesions with 25 cases (5%), then atypical squamous epithelial cells of undetermined significance 14 cases (2.8%), Squamous cell carcinoma 12 cases (2.4%), AGCUS 6 cases (1.2%), AGCUS probably neoplastic origin 1 case (0.2%) and other rare tumors- 1(0.2%)  case of granulosa cell tumor and 1 case(0.2%)  of clear cell carcinoma were seen. The average age of women for all the epithelial abnormalities was 49 years. Conclusion: Pap smear is a simple, cheap, safe and practical diagnostic tool for early detection of cervical cancer in high risk group population, so it should be established as a routine screening procedure. It also has a greater role in diagnosis of inflammatory lesions including the identification of causative organism, atrophic changes, changes of radiation therapy and some rare tumors. It is recommended that at least a single life-time pap screening cytology of uterine cervix of all the women aged 40 to 50 years.

【 授权许可】

CC BY