Profile of PAP smear cytology and its histopathological correlation at tertiary care center – A retrospective study

International Journal of Biomedical and Advance Research

Bhavika Vaghela¹  Pravina M. Santwani¹  Vikas K. Vaghela¹ 

关键词: Pap smear;    Cervical cancer;    The Bethesda System;   

DOI  :  10.7439/ijbar.v5i1.551

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Objective:The Papanicolaou (Pap) smear was introduced in 1941 and became the standard screening test for cervical cancer and premalignant lesions. Cervical cancer is the second most common cancer in women worldwide after breast cancer, and in developing countries, the leading cause of death by cancer. It is one of the most preventable and curable of all cancers. The Pap smear is the standard screening tool used to test for the presence of abnormal cells that could become cancerous. Its role in diagnosis of infective inflammatory conditions is no less successful.Methods:This retrospective study of 500 women with age group 18 to 90 years was carried out over a 2 years at cytology section of pathology department, M.P.Shah medical college, Jamnagar. This study had been divided into 2 groups. Group I included study of 400 women who attended gynaecological clinic at GGH hospital Jamnagar and Group II included study of 100 women who attended Pap smear screening camp ?at Air force hospital, Jamnagar. Results:In group I, maximum number (212) of inflammatory lesions was obtained with incidence of 53%. 84(21%) had SIN, 12(3%) had squamous cell carcinoma. In group II, incidence of normal smear was high. Conclusion:Pap smear is a simple, cheap, safe and practical diagnostic tool for early detection of cervical cancer in high risk group population, so it should be established as a routine screening procedure. It also has a greater role in diagnosis of inflammatory lesions. It is recommended that The Bethesda System should be used for reporting as it improves the reproducibility and helps in identification of ASCUS and AGCUS lesions and plays a key role to diagnose various intraepithelial and invasive lesions at an early stage and manage them ?properly.

【 授权许可】

CC BY