期刊论文详细信息
BMC Health Services Research
Predictors of default from follow-up care in a cervical cancer screening program using direct visual inspection in south-western Nigeria
Per Olof Ostergren2  Innocent Achaya Otobo Ujah1  Olutunmike Kuyoro1  Ifeoma Eugenia Idigbe1  Titilola A Gabajabiamila1  Karen Odberg Petterson2  Oliver Chukwujekwu Ezechi2 
[1] Clinical Sciences Division, Nigerian Institute of Medical Research, Lagos, Nigeria;Social Medicine and Global Health, Faculty of Medicine, Lund University, Lund, Sweden
关键词: Default;    VILI;    VIA;    Direct visual inspection;    Cervical cancer;   
Others  :  1133031
DOI  :  10.1186/1472-6963-14-143
 received in 2013-07-04, accepted in 2014-03-27,  发布年份 2014
PDF
【 摘 要 】

Background

Increasingly evidence is emerging from south East Asia, southern and east Africa on the burden of default to follow up care after a positive cervical cancer screening/diagnosis, which impacts negatively on cervical cancer prevention and control. Unfortunately little or no information exists on the subject in the West Africa sub region. This study was designed to determine the proportion of and predictors and reasons for default from follow up care after positive cervical cancer screen.

Method

Women who screen positive at community cervical cancer screening using direct visual inspection were followed up to determine the proportion of default and associated factors. Multivariate logistic regression was used to determine independent predictors of default.

Results

One hundred and eight (16.1%) women who screened positive to direct visual inspection out of 673 were enrolled into the study. Fifty one (47.2%) out of the 108 women that screened positive defaulted from follow-up appointment. Women who were poorly educated (OR: 3.1, CI: 2.0 – 5.2), or lived more than 10 km from the clinic (OR: 2.0, CI: 1.0 – 4.1), or never screened for cervical cancer before (OR: 3.5, CI:3:1–8.4) were more likely to default from follow-up after screening positive for precancerous lesion of cervix . The main reasons for default were cost of transportation (48.6%) and time constraints (25.7%).

Conclusion

The rate of default was high (47.2%) as a result of unaffordable transportation cost and limited time to keep the scheduled appointment. A change from the present strategy that involves multiple visits to a “see and treat” strategy in which both testing and treatment are performed at a single visit is recommended.

【 授权许可】

   
2014 Ezechi et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150304103904860.pdf 287KB PDF download
Figure 1. 77KB Image download
【 图 表 】

Figure 1.

【 参考文献 】
  • [1]Haghshenas M, Golini-moghaddam T, Rafiee A, Emadeian O, Shykhpour A, Hossein Ashrafi G: Prevalence and type distribution of high-risk human papillomavirus in patients with cervical cancer: a population-based study. Infect Agents Cancer 2013, 8:20. 10.1186/1750-9378-8-20 BioMed Central Full Text
  • [2]Boffetta P, Parkin DM: Cancer in developing countries. CA Cancer J Clin 1994, 44:81-90.
  • [3]Peirson L, Fitzpatrick-Lewis D, Ciliska D, Warren R: Screening for cervical cancer: a systematic review and meta-analysis. Syst Rev 2013, 2:35. doi:10.1186/2046-4053-2-35 BioMed Central Full Text
  • [4]Kitando H: Cancer of the cervix: knowledge and attitudes of female patients admitted at Muhimbili National Hospital, Dar es Salaam. East Afr Med J 2002, 79:467-475.
  • [5]Bingham A, Bishop A, Coffey P, Winkler J, Bradley J, Dzuba I, Agurto I: Factors affecting utilization of cervical cancer prevention services in low resource settings. Salud Publica Mex 2003, 45:S408-S416.
  • [6]Herdman C, Sherris J: Planning appropriate cervical cancer prevention programs. Seattle: Program for Appropriate Technology in Health (PATH); 2000.
  • [7]Pontén J, Adami HO, Bergström R, Dillner J, Friberg LG, Gustafsson L, Miller AB, Parkin DM, Sparén P, Trichopoulos D: Strategies for global control of cervical cancer. Int J Cancer 1995, 60:1-26.
  • [8]Chirenje ZM, Rusakaniko S, Akino V, Mlingo M: A randomised trial of loop electrosurgical excision procedure (LEEP) versus cryotherapy in the treatment of cervical cancer intraepithelial neoplasia. J Obstet Gynaecol 2001, 21:617-621.
  • [9]Holowaty P, Miller AB, Rohan T, To T: Natural history of dysplasia of the uterine cervix. J Natl Cancer Inst 1999, 91:252-268.
  • [10]International Agency for Research on Cancer (IARC) Working Group: Screening for squamous cervical cancer: duration of low risk after negative results of cervical cytology and its implication for screening policies. Br Med J 1986, 293(6548):659-664.
  • [11]Sasieni PD, Cuzick J, Lynch-Farmery E: Estimating the efficacy of screening by auditing smear histories of women with and without cervical cancer. Br J Cancer 1996, 73(8):1001-1005.
  • [12]Federal Ministry of Health: National Policy On Cervical Cancer Prevention And Control. Abuja Nigeria: Federal Ministry of Health in Nigeria; 2011.
  • [13]Sankaranarayanan R, Bhagwan MN, Shastri SS, Jayant K, Muwonge R, Budukh AM, Hingmire S, Malvi SG, Thorat R, Kothari A, Chinoy R, Kelkar R, Kane S, Desai S, Keskar VR, Rajeshwarkar R, Panse N, Dinshaw KA: HPV screening for cervical cancer in rural India. NEJM 2009, 360(14):1385-1394.
  • [14]Ministry of Health: Strategic Plan For Cervical Cancer Prevention And Control In Uganda. Kampala, Uganda: Ministry of Health; 2010.
  • [15]Mwanahamuntu MH, Sahasrabuddhe VV, Kapambwe S, Pfaendler KS, Chibwesha C, Mkumba G, Mudenda V, Hicks ML, Vermund SH, Stringer JS, Parham GP: Advancing cervical cancer prevention initiatives in resource-constrained settings: insights from the cervical cancer prevention program in Zambia. PLoS Med 2011, 8(5):e1001032. doi:10.1371/journal.pmed.1001032
  • [16]Gaffikin L, Blumenthal PD, Emerson M, Limpaphayom K: Safety, acceptability, and feasibility of a single-visit approach to cervical-cancer prevention in rural Thailand: a demonstration project. Lancet 2003, 361:814-820.
  • [17]Sankaranarayanan R, Esmy PO, Rajkumar R, Muwonge R, Swaminathan R, Shanthakumari S, Fayette JM, Cherian J: Effect of visual screening on cervical cancer incidence and mortality in Tamil Nadu, India: a cluster-randomised trial. Lancet 2007, 370:398-406.
  • [18]Anorlu RI: Cervical cancer: the sub-Saharan African perspective. Reprod Health Matters 2008, 16(32):41-49.
  • [19]Mbamara SU, Ukah CO, Ikpeze O, Okonkwo J, Onyiaora V: Correlation between visual inspection of the cervix and pap smear test for cervical cancer screening. J Cancer Res Exp Oncol 2011, 3(1):8-13.
  • [20]Bukar M, Audu BM: Women’s attitude towards cervical cancer screening in North Eastern Nigeria. Nig Med Practioners 2011, 60(1):13-18.
  • [21]Dim CC, Nwagha UI, Ezegwui HU, Dim NR: The need to incorporate routine cervical cancer counseling and screening in the management of women at the outpatient clinics in Nigeria. J Obstet Gynaecol 2009, 29:754-756.
  • [22]Akinola OI, Fabamwo AO, Oshodi YA, Banjo AA, Odusanya O, Gbadegesin A, Tayo A: Efficacy of visual inspection of the cervix using acetic acid in cervical cancer screening: a comparison with cervical cytology. J Obstet Gynaecol 2007, 27:703-705.
  • [23]Ezechi OC, Gab Okafor CV, Ostergren PO, Odberg Petterson K: Willingness and acceptability of cervical cancer screening among HIV positive Nigerian women. BMC Public Health 2013, 13:46. doi:10.1186/1471-2458-13-46 BioMed Central Full Text
  • [24]Horo A, Jaquet A, Ekouevi DK, Toure B, Coffie PA, Effi B, Messou E, Minga A, Moh R, Kone M, Dabis F, Sasco AJ, IeDEA West Africa Collaboration: Cervical cancer screening by visual inspection in Côte d’Ivoire, operational and clinical aspects according to HIV status. BMC Public Health 2012, 12:237. http://www.biomedcentral.com/1471-2458/12/237 webcite BioMed Central Full Text
  • [25]Cárdenas-Turanzas M, Follen M, Benedet J, Scott B: Canto. See-and-treat strategy for diagnosis and management of cervical squamous intraepithelial lesions. Lancet Oncol 2005, 6:43-50.
  • [26]Sankaranarayanan R, Rajkumar R, Esmy PO, Fayette JM, Shanthakumary S, Frappart L, Thara S, Cherian J: Effectiveness, safety and acceptability of ‘see and treat’ with cryotherapy by nurses in a cervical screening study in India. Br J Cancer 2007, 96:738-743.
  • [27]Shah S, Montgomery H, Smith C, Madge S, Walker P, Evans H, Johnson M, Sabin C: Cervical screening in HIV-positive women: characteristics of those who default and attitudes towards screening. HIV Med 2006, 7:46-52.
  • [28]Mutyaba T, Mirembe F, Sandin S, Weiderpas : Evaluation of ‘see-see and treat’ strategy and role of HIV on cervical cancer prevention in Uganda. Reprod Health 2010, 7:4. http://www.reproductive-health-journal.com/content/7/1/4 webcite BioMed Central Full Text
  • [29]Pfaendler KS, Mwanahamuntu MH, Sahasrabuddhe VV, Mudenda V, Stringer JS, Parham GP: Management of cryotherapy-ineligible women in a “screen-and-treat” cervical cancer prevention program targeting HIV- infected women in Zambia: lessons from the field. Gynecol Oncol 2008, 110(3):402-407.
  • [30]Balasubramani L, Orbell S, Hagger M, Brown V, Tify J: Can default rates in colposcopy really be reduced? BJOG 2008, 115(3):403-408.
  • [31]Quinlivan JA, Petersen RW, Gani L, Tan J: Demographic variables routinely collected at colposcopic examination do not predict who will default from conservative management of cervical intraepithelial neoplasia I. Aust N Z J Obstet Gynaecol 2005, 45(1):48-51.
  • [32]Quinlivan JA, Collier RR, Petersen RW: Prevalence and associations of domestic violence at an Australian colposcopy clinic. J Low Genit Tract Dis 2012, 16(4):372-376.
  • [33]World Health Organisation: Prevention of cervical cancer through screening using visual inspection with acetic acid (VIA) and treatment with cryotherapy. A demonstration project in six African countries: Malawi, Madagascar, Nigeria, Uganda, the United Republic of Tanzania, and Zambia. Geneva, Switzerland: World Health Organization; 2012.
  • [34]Kish L: Survey Sampling. New York: John Wiley & Sons, Inc; 1965:41.
  • [35]Ezechi OC, Loto OM, Okogno FO, Ndububa VI, Fasubaa OB: Maternal morbidity and mortality in the south western Nigeria: role of prayer houses Nigerian. J Clin Biomed Res 2012, 6(2):38-42.
  • [36]Adamu YM, Salihu HM: Barriers to the use of antenatal and obstetric care services in rural Kano, Nigeria. J Obstet Gynaecol 2002, 22(6):600-603.
  • [37]Ezechi OC, Fasubaa OB, Dare FO: Socioeconomic barriers to safe motherhood among booked patients in rural Nigerian communities. J Obstet Gynaecol 2000, 20(1):32-34.
  • [38]Ezechi OC, Kalu BK, Ezechi LO, Nwokoro CA, Ndububa VI, Okeke GC: Prevalence and pattern of domestic violence against pregnant Nigerian women. J Obstet Gynaecol 2004, 24:652-656.
  • [39]Ramogola-Masire D, de Klerk R, Monare B, Ratshaa B, Friedman HM, Zetola NM: Cervical cancer prevention in HIV-infected women using the ‘’See and treat” approach in Botswana. J Acquir Immune Defic Syndr 2012, 59(3):308-313.
  • [40]Chibwesha CJ, Cu-Uvin S: See-and-treat approaches to cervical cancer prevention for HIV-infected women. Curr HIV/AIDS Rep 2011, 8(3):192-199.
  • [41]Mutyaba T, Mirembe F, Sandin S, Weiderpass E: Evaluation of ‘see-see and treat’ strategy and role of HIV on cervical cancer prevention in Uganda. Reprod Health 2010, 7:4. 10.1186/1742-4755-7-4 BioMed Central Full Text
  • [42]Denny L, Anorlu R: Cervical cancer in Africa. Cancer Epidemiol Biomarkers Prev 2012, 21:1434-1438.
  • [43]Ngoma T, Muwonge R, Mwaiselage J, Kawegere J, Bukori P, Sankaranarayanan R: Evaluation of cervical visual inspection screening in Dar es Salaam, Tanzania. Int J Gynaecol Obstet 2010, 109(2):100-104.
  • [44]Teguete I, Muwonge R, Traore CB, Dolo A, Bayo S, Sankaranarayanan R: Can visual cervical screening be sustained in routine health services? Experience from Mali, Africa. BJOG 2012, 119(2):220-226.
  • [45]Anderson J, Lu E, Harris M, Kibwana S, Estep D, Varallo J, Coulibaly Toure K, Giattas M: Initial Results from a Multi-country Cervical Cancer Screening Program for HIV + Women. In Proceedings of the 18th Conference on Retroviruses and Opportunistic Infections: 27 February-2 March 2011. Boston, MA; Abstract n°783
  • [46]Kuhn L, Wang C, Tsai WY, Wright TC, Denny L: Efficacy of human papillomavirus-based screen-and-treat for cervical cancer prevention among HIV-infected women. AIDS 2010, 24(16):2553-2561.
  • [47]National Agency for Control of AIDS (NACA): National Hiv/Aids Response Review 2005–09. Abuja Nigeria: NACA; 2011.
  文献评价指标  
  下载次数:20次 浏览次数:12次