Field-Effect Biosensors Modified with Tobacco Mosaic Virus Nanotubes as Enzyme Nanocarrier

Proceedings

Jablonski, Melanie¹ 

关键词: field-effect sensor;    penicillin biosensor;    enzyme penicillinase;    tobacco mosaic virus;    enzyme nanocarrier;   

DOI  :  10.3390/proceedings1040505

学科分类：社会科学、人文和艺术（综合）

来源: mdpi

【 摘 要 】

A new concept for the development of semiconductor field-effect biosensors by modification of a gate surface with tobacco mosaic virus (TMV) nanotubes, serving as enzyme nanocarrier, is presented. TMV nanotubes enable an immobilization of a high amount of enzymes without substantial loss of their activity, resulting in an enhanced biosensor performance. This approach has been experimentally demonstrated by realizing a capacitive field-effect penicillin biosensor using TMV nanotubes functionalized with the enzyme penicillinase as model system.

【 授权许可】

CC BY