Screening for antibacterial, antioxidant activity and toxicity of some medicinal plants used in Benin folkloric medicine

Dynamic Chiropractic

关键词: Antibacterial;    antioxidant;    toxicity;    traditional medicine;    Benin.;   

DOI  :  

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

Ten extracts from 10 medicinal plants,Acanthospermum hispidium,Argemone mexicana,Byrsocarpus coccineus,Canthium setosum,Croton lobatus, Dichapetalum guineense,Nauclea latifolia,Schrankia leptocarpa, Secamone afzelii,Pterocarpus erinaceus,traditionally used in Benin to treat infectious diseases and were screened forin vitroantibacterial activity towardsStaphylococcus aureus,Enteroccocus feacalis,Escherichia coliandPseudomonas aeruginosa.The2, 2-diphenylpicrylhydrazyl radical scavenging activity and toxicity assay usingArtemia salinawere also performed.All extracts were effective against tested microorganisms at different level with MIC ranking from 0.31 to 10 mg/ml.The best inhibition on the growth of tested bacteria was observed with fourextracts obtained fromD. guineense, N. latifolia,andP. erinaceus(MIC = 0.313 mg/ml).The speciesS. aureusandE. faecaliswere more sensitive than the other test bacteria. All extracts showed good radical scavenging activity range from 1.35 to 3.47 µg/ml. The most effective extract was the methanolic extract ofS. leptocarpa, with an EC50value of 1.35 µg/ml. The lethality test showed that all tested extracts have low toxicity against the shrimps with LC50values ranging from 3.8 to 8.17 mg/ml.The results provide an evidence of the traditional use of same collected plants in the treatment of infective diseases.

【 授权许可】

Unknown