Anti-inflammatory properties of ethanolic root extract of Eremurus persicus (Jaub and Spach) Boiss, a Kurdish herbal remedy

Dynamic Chiropractic

#¹  Daniela Rossi#²  Karzan Mahmood Ahmed³  Raffaella Gaggeri⁴  Antonia Avanzini⁵  Ornella Azzolina⁶ 

[1] Center for Studies and Researches in Ethno pharmacy (C.I.St.R.E.), University of Pavia, via Taramelli 12, 27100, Pavia, Italy.;College of Science, Chemistry Department, Karkuk road, University of Salahaddin/Hawler, Kurdistan Region, Iraq.;Department of Chemistry, University of Pavia, Viale Taramelli 12, Pavia 27100, Italy.;Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 12, Pavia 27100, Italy.;Department of Drug Sciences, Pharmacology Section, University of Pavia, Viale Taramelli 12, Pavia 27100, Italy.;Pediatric Hematology/Oncology Department, Fondazione IRCCS Policlinico San Matteo, Piazzale Golgi 19, 27100 Pavia, Italy.

关键词: Anti-inflammatory activity;    Kurdish ethnomedicine;    Eremurus persicus(Jaub and Spach)Boiss;    ethanolic root extract.;   

DOI  :  10.5897/JMPR12.1191

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

This study reports for the first time a preliminary phytochemical and biological screening of ethanolic extract (EE) from roots ofEremurus persicus(Jaub and Spach) Boiss, a Kurdish herbal remedy for treating inflammatory disorders. The phytochemical analysis was performed by thin layer chromatography and it revealed the presence of flavonoids and antracenones. The total phenolic compounds were also determined. Free radical scavenging (FRS) effect was evaluated by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay and the anti-inflammatory activity investigated by evaluating the inhibition ofin vitrolymphocyte proliferation. To exclude citotoxic effect of EE, cell viability tests were also performed. Overall, biological investigation showed that theE. persicus(Jaub and Spach) Boissroot EE possess an interesting anti-inflammatory activity without cytotoxic effects.

【 授权许可】

Unknown