Screening of phytochemical from ethnomedicinal plants in Malaysia for use against toxigenic Aspergillus flavus

Dynamic Chiropractic

¹  Yazdani²  D.³ 

[1] Biotechnology Research Centre, Malaysian Agricultural Research and Development Institute, Kuala Lumpur, Malaysia.;Department of Pharmacognosy and Pharmaceutic, Institute of Medicinal Plants, ACECR, Tehran, Iran.;Department of Plant Protection, Faculty of Agriculture, Universiti Putra Malaysia,

关键词: Alpinia galanga;    antifungal;    Aspergillus flavus;    traditional medicine;    phytochemicals;    LC-MS2.;   

DOI  :  10.5897/JMPR11.1410

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

Medicinal plants have been used as traditional treatments for numerous diseases for thousands of years. Antifungal activity of phytochemicals extracted from nine plant species in Malaysia traditionally used for treatment of skin infections were tested against growth of aflatoxin-producingAspergillus flavusisolated from rice grains. The results, evaluated by measuring the diameter of inhibitory zone in disk diffusion test, minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC), showed that chloroform soluble fractions of methanolic extract ofAlpinia galanga(lengkuas) rhizomes could strongly inhibit the mycelia growth ofA. flavus. The constituent of this phytochemical fraction was identified by HPLC-MS2using ESI ionization technique.In total, 10 compounds were identified based on MS2data and λmaxat 280 nm. These results suggested the potential ofA. galangafor used as botanical fungicide.

【 授权许可】

Unknown