Does Helicobacter pylori Infection Play a Role in Susceptibility to Brucellosis?

Japanese journal of infectious diseases

Sara Nadri¹  Ebrahim Ghaderi²  Katayon Hajibagheri³  Behzad Mohsenpour⁴  Shahla Afrasiabian⁴ 

[1] Epidemiology and Biostatistics Department, School of Medicine, Kurdistan University of Medical Sciences;Social Determinants of Health Research Center, Kurdistan University of Medical Sciences;Student Research Committee, Kurdistan University of Medical Sciences;Zoonoses Research Center, Kurdistan University of Medical Sciences

关键词: brucellosis;    Helicobacter pylori;    Kurdistan;   

DOI  :  10.7883/yoken.JJID.2017.043

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

Brucellosis is endemic in Iran. Several studies have shown that brucellosis is associated with other infectious diseases. This study aimed to determine the relationship between Helicobacter pylori (HP) and brucellosis. In this case-control study, 100 patients with brucellosis as cases and 200 participants without brucellosis as controls were evaluated. To compare the prevalence of HP in the 2 groups, odds ratios and confidence intervals for every variable were analyzed using logistic regression models after adjustment for confounding factors. The results obtained in patients with brucellosis showed that fever, sweating, and joint pain were the most prevalent clinical symptoms. In addition, compared with the control group, there was a significant relationship between the IgM antibody to HP and brucellosis infection (estimated odds ratio 2.74; 95% CI: 1.5–4.9) (p = 0.001). Acute infection with HP was associated with brucellosis and increased the risk of brucellosis infection.

【 授权许可】

Unknown