Epidemiology of Respiratory Pathogens in Children with Lower Respiratory Tract Infections in Shanghai, China, from 2013 to 2015

Japanese journal of infectious diseases

Pengcheng Liu¹  Menghua Xu¹  Lijuan Lu¹  Liyun Su¹  Leiyan He¹  Jin Xu¹  Aimin Wang¹  Pan Fu¹  Chuanqing Wang¹ 

[1] Department of Clinical Laboratory, Children’s Hospital of Fudan University

关键词: aetiology;    children;    epidemiology;    lower respiratory tract infection;    respiratory pathogen;   

DOI  :  10.7883/yoken.JJID.2017.323

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

This study aimed to explore the epidemiology of pathogens in children who were hospitalized with lower respiratory tract infections (LRTIs) at the Children’s Hospital of Fudan University, Shanghai, China. Children aged less than 18 years who were hospitalized with LRTIs were enrolled from January 2013 to December 2015. Respiratory specimens were collected for the detection of common respiratory viruses, atypical bacteria, and other bacteria using current laboratory diagnostic tests. The epidemiological characteristics of the respiratory pathogens were analyzed. Of the 10,123 specimens obtained from the patients, 5,966 (58.7%) were positive for at least 1 pathogen. Mycoplasma pneumoniae (M.pneumoniae) was the most commonly detected pathogen (15.7%), followed by respiratory syncytial virus (RSV) (13.9%). Co-infections were found in 11.4% of patients. Of these co-infections, viral-bacterial co-infections were the most common. The detection rates for the respiratory pathogens varied considerably by age. RSV was the most common pathogen in children aged less than 24 months. Clear seasonal peaks were observed for RSV, M. pneumoniae, parainfluenza virus, human metapneumovirus, Moraxella catarrhalis, and Haemophilus influenza infections. Our findings demonstrate specific epidemiological patterns in children with LRTIs in Shanghai, China.

【 授权许可】

Unknown