SOLVENT-FREE C-ALKYLATION OF BARBITURIC ACID IN THE NANOCRYSTALLINE MORDENITE MEDIA

Journal of The Chilean Chemical Society

ZAMANLOO, MOHAMMADREZA¹  MANSOORI, YAGOUB¹  TAGHAVI, SAEED¹  KABIRI, SAEED¹  IMANZADEH, GHOLAMHASSAN¹ 

[1] University of Mohaghegh Ardabili, Ardabil, Iran

关键词: Solvent-;    free;    C-;    Alkylation;    Barbituric Acid;    α;    β;    -;    UnsaturatedEsters;    Nano-;    Mordenite (Nano-;    MOR).;   

DOI  :  10.4067/S0717-97072013000300021

学科分类：化学（综合）

来源: Sociedad Chilena de Quimica

【 摘 要 】

A simple, efficient and cleanprocedure has been developed for the C-alkylation of barbituricacid. The Michael addition of barbituric acid to α,β-unsaturatedesters by employing K2CO3 in the nano-mordenite media(K2CO3/nano-MOR), as catalyst, gave C-alkylatedbarbituric acid in good to excellent yield. Nano-MOR showed good reusability.K2CO3/nano-MOR catalyst has been found to be an excellentcatalyst for the reaction under solvent-free conditions at 80-90 °C.

【 授权许可】

Unknown