AN ECO-FRIENDLY ONE-POT SYNTHESIS OF 4,4'-(ARYLMETHYLENE)BIS(1H-PYRAZOL-5-OLS) USING [Et3NH][HSO4] AS A RECYCLABLE CATALYST

Journal of The Chilean Chemical Society

ZHOU, ZHONGQIANG¹  ZHANG, YULIANG¹ 

[1] South-Central University for Nationalities, Wuhan, China

关键词: 4;    4'-;    (Arylmethylene)bis(1H-;    pyrazol-;    5-;    ols);    [;    Et3NH];    [;    HSO4];    Solvent-;    free;    Multicomponent reaction;   

DOI  :  10.4067/S0717-97072015000300003

学科分类：化学（综合）

来源: Sociedad Chilena de Quimica

【 摘 要 】

A simple and efficient procedure for synthesis of 4,4'-(arylmethylene)bis(1H-pyrazol-5-ols) by one-pot three-component condensation of aromatic aldehydes, ethyl acetoacetate, and phenylhydrazine/hydrazine hydrate under solvent-free conditions in the presence of [Et3NH][HSO4] as catalyst is described. The present protocol offers several advantages such as using a reusable and cost-effective ionic liquid, high yields, simple procedure, easy work-up and eco-friendly reaction conditions.

【 授权许可】

Unknown