HIGHLY EFFICIENT AND VERSATILE ACETYLATION OF ALCOHOLS, PHENOLS AND AMINES CATALYZED BY METHYLENEDIPHOSPHONIC ACID (MDP) UNDER SOLVENT-FREE CONDITIONS

Journal of The Chilean Chemical Society

WU, JUN¹  XIE, MINHAO¹  WANG, HONGYONG¹  LIU, YALING¹  ZOU, PEI¹  HE, YONGJUN¹ 

[1] Jiangsu Institute of Nuclear Medicine, Wuxi, China

关键词: Bisphosphonic acid;    MDP;    Solvent-;    free;    Acetylation.;   

DOI  :  10.4067/S0717-97072011000400013

学科分类：化学（综合）

来源: Sociedad Chilena de Quimica

【 摘 要 】

Methylenediphosphonic Acid (MDP) was found to be a simple, cheap and reusable heterogeneous catalyst for the acetylation of structurally diverse alcohols, phenols and amines with acetic anhydride under solvent-free conditions at room temperature. This method showed preferential selectivity for the acetylation of the amino group in the presence of hydroxyl group. The method is very mild and the yields were in excellent.

【 授权许可】

Unknown