Spectrophotometric study of the solution interactions between riboflavin, sodium salicylate and caffeine

International Journal of Physical Sciences

Bolotin P. A.¹ 

关键词: Spectrophotometry;    riboflavin;    caffeine;    nicotinamide;    urea;    hetero-association;   

DOI  :  

学科分类：物理（综合）

来源: Academic Journals

【 摘 要 】

The self-association of Vitamin B2(Riboflavin, RBF) and its hetero-association with Sodium Salicylate (NAS) and Caffeine (CAF) have been studied in aqueous solution by UV-Vis spectrophotometry. Using modified Benesi-Hildebrand approach equilibrium hetero-association constants were obtained for RBF-NAS [K = (25±4) M-1] and RBF-CAF [K = (69±4) M-1] systems at T = 298K. Absorption spectra of the vitamin in the mixed solutions with CAF/NAS evidence a bathochromic and hyperchromic shifts which are indicative of the hetero-association process between the dissolved molecules, most likely occurring via vertical stacking of their chromophores. Addition of Urea to the solutions of RBF-NAS and RBF-CAF decreases the stability of the hetero-complexes downto K = (17±3) M-1and K = (51±7)M-1, respectively.

【 授权许可】

CC BY