Upregulation of lncRNA BANCR associated with the lymph node metastasis and poor prognosis in colorectal cancer

Biological research: BR

Xiaogang Shen¹  Bin Luo³  Yifeng Bai⁴  Xiaogang Zhou⁴ 

[1] Department of Gastrointestinal Surgery, Sichuan Academy of Medical Sciences and Sichuan Provincial People’Department of Gastrointestinal Surgery, Sichuan Provincial People’Department of Oncology, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, Chengdu, China

关键词: lncRNA;    BANCR;    Colorectal cancer;    Lymph node metastasis;    Prognosis;   

DOI  :  10.1186/s40659-017-0136-5

学科分类：生物科学（综合）

来源: BioMed Central

【 摘 要 】

Growing evidence has supported that long non-coding RNAs (lncRNAs) could play vital roles in the development, progression, and prognosis of colorectal cancer (CRC). However, little is known about the clinical significance of BRAF-activated non-coding RNA (BANCR) in CRC. The aim of this study is to explore the clinical value of lncRNA BANCR in CRC patients. The expression of lncRNA BANCR was measured in 106 CRC tissues and 65 adjacent normal tissues using the quantitative real-time PCR. The study showed that lncRNA BANCR was highly expressed in CRC tissues compared with adjacent normal tissues (P 

【 授权许可】

CC BY