Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains

PLoS Pathogens

Géraldine Verney¹  Judith Fresquet¹  Dimitri Lavillette¹  Zélie Julia³  Viet Loan Dao Thi³  Fabien Zoulim³  François-Loïc Cosset⁵  Birke Bartosch⁵  David Durantel⁶  Maryse Guérin⁶  Marlène Dreux⁶ 

[1] EcoleNormale Supérieure de Lyon, Lyon, France;Hospicescivils de Lyon (HCL), Lyon, France;INSERM, U758;INSERM, U871;INSERM, U551, Paris, France;Université de Lyon, UCB-Lyon1, IFR128;Université de Lyon, UCB-Lyon1, IFR62

关键词: Hepatitis C virus;    Cholesterol;    Lipids;    Cell binding;    Virus glycoproteins;    Cell membranes;    Virions;    Lipid mediators;   

DOI  :  10.1371/journal.ppat.1000310

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

CC BY