Status of Dyslipidemia Management with Statins, in In-patients with known Coronary Artery Disease confirmed by angiographic findings

International Journal of Biomedical Research

Ushakiran P¹  Baruah DK¹  Sudhakar K¹  Srinivas A.¹  Sudha J¹  Vijay T² 

[1] Department of Cardiology, Apollo Hospitals, Visakhapatnam;Department of Pharmacology, Andhra medical college, Visakhapatnam

关键词: Coronary artery disease;    Dyslipidemia;    Statins;   

DOI  :  10.7439/ijbr.v8i7.4248

学科分类：基础医学

来源: Scholar Science Journals

【 摘 要 】

Aim: To determine the status of dyslipidemia management with statins in In-patients with known Coronary Artery Disease (CAD) confirmed by angiographic findings.Methods: This study has been conducted in a corporate cardiac centre at Visakhapatnam, Andhra Pradesh. This study is a retrospective analysis of data collected from the electronic medical records in terms of age, sex, CAD status, associated risk factors, statin usage, and lipid parameters.Results: Among a sample of 92 known CAD in-patients, 81.5% achieved LDL-C goal of <100 mg/dl as recommended by Third Report of the National Cholesterol Education Program (NCEP) Adult Treatment Panel III [ATP III] for CAD and CAD risk equivalents. Success rates among males and females are 79.7% and 85% respectively. 78.2% of 69 patients on Atorvastatin, 85% of 20 patients on Rosuvastatin and 100% of 3 patients on Simvastatin achieved LDL-C goal. If the target LDL-C level is kept at <70 mg/dl as defined as optional goal for very high risk CAD and CAD risk equivalents, the success rate is only 31.5%.Conclusion: The Success rates for achieving LDL-C goals (<100mg/dl) is satisfactory in this facility. But the major concern in this study is even with desired LDL-C levels 61% of these in-patients suffered with a recurrent CAD leaving an opportunity to reconsider the target LDL-C to still lower levels (<70 mg/dl) which is mentioned just as an optional for very high risk candidates in NCEP ATP-III guidelines.

【 授权许可】

CC BY