Influenza A Virus on Oceanic Islands: Host and Viral Diversity in Seabirds in the Western Indian Ocean

PLoS Pathogens

Nirmal Shah¹  Thierry Boulinier¹  Camille Lebarbenchon¹  Chris Feare¹  Erwan Lagadec¹  David E. Stallknecht²  Koussay Dellagi³  Gérard Rocamora⁴  Muriel Dietrich⁴  Matthieu Le Corre⁵  Audrey Jaeger⁵  Matthieu Bastien⁵  Christine Larose⁶  Hervé Pascalis⁶ 

[1] GIS CRVOI (Centre de Recherche et de Veille sur les maladies émergentes dans l'Océan Indien), Sainte Clotilde, Reunion Island;Institut de Recherche pour le Développement, Sainte Clotilde, Reunion Island;Island Conservation Society, Mahé, Seychelles;Laboratoire d'Ecologie Marine, FRE 3560 INEE-CNRS, Université de La Réunion, Saint Denis, Reunion Island;Université de La Réunion, UMR PIMIT (Processus Infectieux en Milieu Insulaire Tropical), INSERM 1187, CNRS 9192, IRD 249, Saint Denis, Reunion Island;WildWings Bird Management, Grayswood Common, Haslemere, Surrey, United Kingdom

关键词: Influenza A virus;    Isl;    s;    Birds;    Seabirds;    Animal migration;    Ducks;    Indian Ocean;    Animal sexual behavior;   

DOI  :  10.1371/journal.ppat.1004925

学科分类：生物科学（综合）

来源: Public Library of Science

【 摘 要 】

Ducks and seabirds are natural hosts for influenza A viruses (IAV). On oceanic islands, the ecology of IAV could be affected by the relative diversity, abundance and density of seabirds and ducks. Seabirds are the most abundant and widespread avifauna in the Western Indian Ocean and, in this region, oceanic islands represent major breeding sites for a large diversity of potential IAV host species. Based on serological assays, we assessed the host range of IAV and the virus subtype diversity in terns of the islands of the Western Indian Ocean. We further investigated the spatial variation in virus transmission patterns between islands and identified the origin of circulating viruses using a molecular approach. Our findings indicate that terns represent a major host for IAV on oceanic islands, not only for seabird-related virus subtypes such as H16, but also for those commonly isolated in wild and domestic ducks (H3, H6, H9, H12 subtypes). We also identified strong species-associated variation in virus exposure that may be associated to differences in the ecology and behaviour of terns. We discuss the role of tern migrations in the spread of viruses to and between oceanic islands, in particular for the H2 and H9 IAV subtypes.

【 授权许可】

CC BY