Blainvillea rhomboidea: chemical constituents and cytotoxic activity

Quimica nova

Santos, Hélcio Silva dos¹  Gomes, Regina Ferreira¹  Albuquerque, Maria Rose Jane R.¹  Pessoa, Otília Deusdênia L.²  Rodrigues, Felipe A. R.²  Lotufo, Leticia V. Costa²  Moraes, Manoel Odorico de²  Pessoa, Claudia do Ó² 

[1] Universidade Estadual Vale do Acaraú, Sobral, Brasil;Universidade Federal do Ceará, Fortaleza, Brasil

关键词: Blainvillea rhomboidea;    Asteraceae;    flavonoids.;   

DOI  :  10.1590/S0100-40422010000500022

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

The phytochemicalinvestigation of the ethanol extract from the aerial parts of Blainvillearhomboidea (Asteraceae) resulted in the isolation and characterization of8β-tigloyloxy-grazieliaacid, together with the flavonoids derrone, acacetin, luteolin and luteolin7-methyl ether, and p-(1-methyl-ethan-1-ol)-phenol. The structures ofall compounds were determined by spectroscopic methods (1H and 13CNMR and HREIMS) and comparison with published spectral data. The flavonoidsluteolin and 7-O-metyl-luteolin, isolated from the active dichloromethane fraction,showed moderate cytotoxic activity.

【 授权许可】

CC BY