Blainvillea rhomboidea: constituintes químicos e atividade citotóxica

Química Nova

Regina Ferreira Gomes²  Hélcio Silva Dos Santos²  Maria Rose Jane R. Albuquerque²  Otília Deusdênia L. Pessoa¹  Leticia V. Costa Lotufo¹  Claudia Do Ó Pessoa¹  Manoel Odorico De Moraes¹  Felipe A. R. Rodrigues¹ 

[1] ,Universidade Estadual Vale do Acaraú Centro de Ciências Exatas e Tecnologia Sobral CE ,Brasil

关键词: Blainvillea rhomboidea;    Asteraceae;    flavonoids;   

DOI  :  10.1590/S0100-40422010000500022

来源: SciELO

【 摘 要 】

The phytochemical investigation of the ethanol extract from the aerial parts of Blainvillea rhomboidea (Asteraceae) resulted in the isolation and characterization of 8β-tigloyloxy-grazielia acid, together with the flavonoids derrone, acacetin, luteolin and luteolin 7-methyl ether, and p-(1-methyl-ethan-1-ol)-phenol. The structures of all compounds were determined by spectroscopic methods (¹H and 13C NMR and HREIMS) and comparison with published spectral data. The flavonoids luteolin and 7-O-metyl-luteolin, isolated from the active dichloromethane fraction, showed moderate cytotoxic activity.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License