Antioxidant effect of garlic (Allium sativum) and black seeds (Nigella sativa) in healthy postmenopausal women:

SAGE Open Medicine

Randa MMostafa¹ 

关键词: Menopause;    oxidative stress;    garlic;    antioxidants;    superoxide dismutase;    malondialdehyde;    oxidation;   

DOI  :  10.1177/2050312113517501

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Objectives:The objective of this study is to investigate the antioxidant effects of garlic extract and crude black seeds’ consumption on blood oxidant/antioxidant levels in healthy postmenopausal women.Methods:In total, 30 healthy postmenopausal women (mean age = 50.31 ± 4.23 years) participated. They ingested two garlic soft gels per day (each is equivalent to 1000 mg of fresh garlic bulb) and crude black seed grounded to powder in a dose of 3 g/day for 8 weeks. Oxidant (malondialdehyde) activity in plasma and antioxidants superoxide dismutase and glutathione peroxidase activities in erythrocytes were studied.Results:Significant low levels of plasma malondialdehyde with increased erythrocyte glutathione peroxidase and superoxide dismutase activities.Discussion:Menopause is associated with an increase in oxidative stress and a decrease in some antioxidant parameters. Consumption of garlic extracts and crude black seeds may have a beneficial effect on improved balance between blood oxidants and antioxidant...

【 授权许可】

CC BY