Eosinophilic Esophagitis: An Emerging Disease in Childhood – Review of Diagnostic and Management Strategies

Frontiers in Pediatrics

Alex¹ 

关键词: eosinophilic esophagitis;    oral viscous budesonide;    fluticasone propionate;    oral steroids;    amino acid-based formula;    empiric elimination diet;    targeted elimination diet;   

DOI  :  10.3389/fped.2014.00129

学科分类：儿科学

来源: Frontiers

【 摘 要 】

Eosinophilic esophagitis is a chronic immune/antigen mediated inflammatory disease of the esophagus. It comprises a separate entity of increasing incidence and prevalence in children and adults. The disease is characterized by histological evidence of dense esophageal tissue eosinophilia in the presence of a variety of upper GI symptoms including vomiting, dysphagia, food impaction, and odynophagia. Cornerstone of treatment is dietary intervention and/or the off-label use of swallowed topical corticosteroids. New drug therapies are under investigation. In this review, we focus on the diagnostic approach and the currently available treatment strategies.

【 授权许可】

CC BY