Comment on Casiraghi et al. “Mucoadhesive Budesonide Formulation for the Treatment of Eosinophilic Esophagitis” 2020, 12, 211

Pharmaceutics

Eyal Zur¹ 

[1] Pharmaceutical Compounding Consultancy Agency: “Compounding Solutions”, Tel-Mond 4062269, Israel;

关键词: eosinophilic esophagitis;    oral viscous budesonide;    compounding;    compounding pharmacist;   

DOI  :  10.3390/pharmaceutics12090829

来源: DOAJ

【 摘 要 】

In their article, Casiraghi, A. et al. describe a few relevant methods to assess the quality of a pharmaceutical preparation of oral viscous budesonide, intended to be swallowed, and treat the esophagus in eosinophilic esophagitis patients. They choose the following methods for this purpose: rheological properties, syringeability, mucoadhesiveness, and in vitro penetration of budesonide in porcine esophageal tissue. At the end of the article, they concluded that the best formulation of oral viscous budesonide was the one already being used in hospitals, based on xanthan gum. In their article, the authors did not emphasize that this specific formula was developed by the compounding pharmacist Eyal Zur from Israel and was published eight years before, as part of an article in the International Journal of Pharmaceutical Compounding. The purpose of this comment is to give the appropriate credit to the pharmacist who first developed and published this well designed formulation.

【 授权许可】

Unknown