A retrospective epidemiologic study to define risk factors, microbiology, and clinical outcomes of infective endocarditis in a large tertiary-care teaching hospital:

SAGE Open Medicine

Anahita SMostaghim¹ 

关键词: Infective endocarditis;    epidemiology;    outcomes;    hemodialysis;    microbiology;    risk factor;    mortality;   

DOI  :  10.1177/2050312117741772

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Objective:This study aims to define risk factors as well as their association with microbiology and clinical outcomes in a large US infective endocarditis population.Methods:Hospital records were searched for appropriate infective endocarditis–related ICD codes from 16 July 2007 to 13 August 2015. A total of 363 cases were retrospectively identified that met definite Modified Duke Criteria for infective endocarditis and were analyzed by age group, causative organism, and associated risk factors for use of valvular surgical intervention, 30/90/180-day mortality after admission, and embolic phenomena.Results:Chronic hemodialysis was the most common risk factor (26.7% of cases). Of all age groups, those aged 78+ years had the lowest 30-day mortality but those aged 58–77 years had the highest mortality (p = 0.039). Staphylococcus aureus was the most prevalent causative organism. Those aged 78–97 years were more likely to have enterococcal infective endocarditis than those aged 18–27 years (p = 0.0144). Chroni...

【 授权许可】

CC BY