Active Trachoma Cases in the Solomon Islands Have Varied Polymicrobial Community Structures but Do Not Associate with Individual Non-Chlamydial Pathogens of the Eye

Frontiers in Medicine

Robert M. R. Butcher¹ 

关键词: droplet digital PCR;    Solomon Islands;    16S rRNA gene sequencing;    trachoma;    non-chlamydial infections;   

DOI  :  10.3389/fmed.2017.00251

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

BackgroundSeveral non-chlamydial microbial pathogens are associated with clinical signs of active trachoma in trachoma-endemic communities with a low prevalence of ocular Chlamydia trachomatis (Ct) infection. In the Solomon Islands, the prevalence of Ct among children is low despite the prevalence of active trachoma being moderate. Therefore, we set out to investigate whether active trachoma was associated with a common non-chlamydial infection or with a dominant polymicrobial community dysbiosis in the Solomon Islands.

【 授权许可】

CC BY