Effects of subthalamic nucleus deep brain stimulation on quality of life and motor and depressive symptoms in Parkinson's disease

Tzu-Chi Medical Journal

Jiin-Ling Jiang¹ 

关键词: Parkinson's disease;    Quality of life;    Subthalamic nucleus stimulation;    Symptoms;   

DOI  :  

学科分类：医学（综合）

来源: Wolters Kluwer Medknow Publications

【 摘 要 】

The objective of this paper is to review the available literature concerning the effects of subthalamic nucleus deep brain stimulation (STN-DBS) on quality of life (QoL) and motor and depressive symptoms in patients with Parkinson's disease (PD). These studies demonstrate that STN-DBS has an effect on QoL and symptoms in patients with PD. There was a significant improvement in QoL following STN-DBS compared with no improvement after medical therapy. PD patients treated with STN-DBS had a 40–50% improvement in motor function. Nevertheless, depressive symptoms did not reveal consistent change.

【 授权许可】

CC BY-NC-SA