Fabrication and Characterization of an OTFT-Based Biosensor Using a Biotinylated F8T2 Polymer

ETRI Journal

关键词: biosensor;    biotin;    avidin;    F8T2;    polymer;    OTFTs;    Organic semiconductor;   

Others  :  1185735
DOI  :  10.4218/etrij.09.1209.0001

【 摘 要 】

Solution-processable organic semiconductors have been investigated not only for flexible and large-area electronics but also in the field of biotechnology. In this paper, we report the design and fabrication of biosensors based on completely organic thin-film transistors (OTFTs). The active material of the OTFTs is poly(9,9-dioctylfluorene-co-bithiophene) (F8T2) polymer functionalized with biotin hydrazide. The relationship between the chemoresistive change and the binding of avidin-biotin moieties in the polymer is observed in the output and on/off characteristics of the OTFTs. The exposure of the OTFTs to avidin causes a lowering of ID at VD = -40 V and VG = -40 V of nearly five orders of magnitude.

   

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