Efficacy and safety of iota-carrageenan nasal spray versus placebo in early treatment of the common cold in adults: the ICICC trial

Respiratory Research

S. Koelsch⁵  M. Trampisch¹  P. Robinson⁶  S.L. Johnston²  B. Winther³  R. Eccles⁴ 

[1] Boehringer Ingelheim Pharma GmbH & Co. KG, Biometrics & Data Management, Ingelheim/Rhein 55216, Germany;Airway Disease Infection Section & MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, National Heart and Lung Institute, Imperial College, London, UK;Respiratory Disease Study Center, University of Virginia, Charlottesville, VA, USA;Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK;Boehringer Ingelheim Pharma GmbH & Co. KG, CHC Development, Medicine & Regulatory Affairs, Ingelheim/Rhein 55216, Germany;Boehringer Ingelheim Pharmaceuticals Inc., Therapeutic Area Virology, Ridgefield, CT, USA

关键词: Clinical trial;    Human rhinovirus;    Common cold;    Iota-carrageenan;   

Others  :  1233514
DOI  :  10.1186/s12931-015-0281-8

 received in 2015-06-17, accepted in 2015-09-18,  发布年份 2015

【 摘 要 】

Iota-carrageenan (I-C) is active against respiratory viruses in vitro and was effective as nasal spray in three previous clinical trials. The current trial served to further investigate I-C in patients with early common cold symptoms.

【 授权许可】

   
2015 Eccles et al.

【 图 表 】

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